Quiet 50 XR | Atypical neuroleptic drugs
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Home Medicines Mental Disorder Quiet 50 XR Tablet 10pcs
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Quiet 50 XR Tablet 10pcs

Generic: Quetiapine

Type: Tablet

Pack Size: 10 Pcs

Quiet 50 XR Tablet is used to manage:

  • Bipolar disorder
  • Schizophrenia
  • Depression (major depressive disorders)

How to Order

🛒 How to order this item?

Prescription Required
Discount Price: ৳ 75.2
MRP: ৳ 80 6% Off

⪼ Save  ৳: 4.8  in this Product


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✅ Description:

Quetiapine is used to treat various mental health conditions, including:

  1. Schizophrenia: A mental disorder that affects a person’s ability to think, feel, and behave clearly.
  2. Bipolar Disorder: A condition characterized by mood swings that include emotional highs (mania or hypomania) and lows (depression).
    • Manic Episodes: Periods of abnormally elevated mood and energy levels.
    • Depressive Episodes: Periods of intense sadness or despair.
  3. Major Depressive Disorder (MDD): Used as an adjunct treatment for patients not responding to standard antidepressants.
  4. Prevention of Recurrence: Helps in preventing recurrence of depressive episodes in bipolar disorder.

Safety Advices


Alcohol
UNSAFE

It is unsafe to consume alcohol while taking Quiet 50 XR tablets. Alcohol can increase the side effects of Qutipin, such as drowsiness, dizziness, and impaired judgment.


Pregnancy
UNSAFE

Quiet 50 XR Tablet may be unsafe to use during pregnancy. While there are limited studies in humans, animal studies have shown potential harmful effects on the developing baby. Your doctor will evaluate the benefits and risks before prescribing this medication to you. Please consult your doctor for personalized advice.


Breastfeeding
CONSULT YOUR DOCTOR

Quiet 50 XR Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into breastmilk and could harm the baby. It is important to consult your doctor before taking this medication if you are breastfeeding.


Driving
UNSAFE

Quiet 50 XR Tablet may reduce alertness, impair vision, or cause drowsiness and dizziness. Do not drive or operate heavy machinery if you experience these symptoms.


Kidney
CAUTION

Quiet 50 XR Tablet is probably safe to use in patients with kidney disease. Limited data suggests that dose adjustment may not be necessary in these patients. However, it is crucial to consult your doctor for personalized advice.


Liver
CONSULT YOUR DOCTOR

Quiet 50 XR Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed for these patients. Please consult your doctor to determine the appropriate dosage and to monitor liver function during treatment.

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✔️ Uses of Quiet 50 XR Tablet

It is used to manage:

  • Bipolar disorder
  • Schizophrenia
  • Depression (major depressive disorders)
✔️ How does Quiet 50 XR Tablet work?

It works by helping to restore the balance of certain natural substances (neurotransmitters) such as Serotonin and Dopamine in the brain. Increased levels of these substances may cause depression or mood swings.

✔️ Side Effects

Common side effects of Quetiapine include:

General:

  • Dizziness, weakness, drowsiness
  • Withdrawal symptoms (nausea, vomiting, diarrhea, irritability)

Cardiovascular:

  • Low blood pressure
  • Rapid heartbeat
  • Fainting

Neurological:

  • Seizures
  • Symptoms of neuroleptic malignant syndrome (high fever, muscle stiffness, confusion)

Psychological:

  • Nightmares, unpleasant dreams, suicidal thoughts
  • Worsening symptoms (anxiety, panic attacks, irritability, agitation, aggressiveness)

Metabolic:

  • Weight gain, increased appetite
  • Changes in blood levels (e.g., elevated blood sugar, elevated liver enzymes)
  • Metabolic syndrome (increase in abdominal fat, decreased HDL cholesterol, high blood pressure, elevated blood glucose, elevated triglycerides)

Gastrointestinal:

  • Difficulty passing urine
  • Nausea, vomiting, diarrhea

Other:

  • Blurred vision, difficulty speaking
  • Swelling of hands and legs
  • Stuffy nose
  • Allergic reactions (itching, hives, rash, swelling of lips, face, throat)
  • Liver issues (jaundice, liver disease)
  • Formation of blood clots
  • Restless legs syndrome
  • Low body temperature (hypothermia)
✔️ Quick Suggestions:
  • Take Quetiapine with or without food, as instructed by your doctor.
  • It is used for long-term treatment. Hence avoid discontinuing this medicine without consulting your doctor as your condition may become worse. Also, you may experience withdrawal symptoms such as trouble sleeping, irritability, diarrhea, headache, etc.
  • Your doctor may recommend periodic blood tests to monitor your blood sugar and cholesterol levels during treatment with this medicine.
  • Quetiapine may cause drowsiness or dizziness. Hence, avoid driving vehicles or operating machines if you experience such symptoms after taking this medicine.
  • Drink plenty of water and avoid getting dehydrated while you are taking this medicine.
  • Also, avoid doing strenuous exercise or getting exposed to extreme heat. This medicine may impair the body's ability to regulate body temperature.
  • Consult your doctor immediately if you experience mood changes or thoughts of self-harm.
✔️ Indications:

Quiet XR is indicated for the treatment of acute and chronic psychoses, including schizophrenia, and bipolar disorder. This includes:

  • Treatment of manic episodes in bipolar disorder
  • Treatment of depressive episodes in bipolar disorder
  • Maintenance treatment of bipolar I disorder, in combination with a mood stabilizer, to prevent recurrence of manic, depressive, or mixed episodes.
✔️ Pharmacology

Quetiapine Fumarate is an atypical psychotropic agent belonging to the dibenzothiazepine derivatives. It acts as an antagonist at multiple neurotransmitter receptors, including serotonin 5HT1A and 5HT2, dopamine D1 and D2, histamine H1, and adrenergic α1 and α2 receptors. It has no appreciable affinity for cholinergic muscarinic and benzodiazepine receptors. The efficacy in schizophrenia is believed to be mediated through dopamine D2 and serotonin 5HT2 antagonism. Its antagonism of histamine H1 receptors may explain somnolence, and adrenergic α1 receptor antagonism may explain orthostatic hypotension.

✔️ Dosage & Administration of Quiet 50 XR Tablet

Dosage & Administration:

Schizophrenia:

  • Administer twice daily, with or without food.
  • Day 1: 50 mg, Day 2: 100 mg, Day 3: 200 mg, Day 4: 300 mg.
  • The usual effective dose range: is 300-450 mg/day, adjustable within 150-750 mg/day based on response and tolerability.

Manic episodes in bipolar disorder:

  • Administer twice daily, with or without food.
  • Day 1: 100 mg, Day 2: 200 mg, Day 3: 300 mg, Day 4: 400 mg.
  • Dosage adjustments up to 800 mg/day by Day 6 in increments no greater than 200 mg/day.
  • Effective dose range: 400-800 mg/day.

Depressive episodes in bipolar disorder:

  • Administer once daily at bedtime, with or without food.
  • Day 1: 50 mg, Day 2: 100 mg, Day 3: 200 mg, Day 4: 300 mg.
  • Can be titrated to 400 mg on Day 5 and up to 600 mg by Day 8.
  • Effective dose range: 300-600 mg/day.

Maintenance in bipolar I disorder:

  • Continue the same dose as in acute treatment with a mood stabilizer.
  • The dose can be adjusted based on response and tolerability.
  • Effective combination therapy dose: 400-800 mg/day.
  • Elderly: Use with caution, slower dose titration, and lower daily dose.
  • Children and Adolescents: Not indicated for use below 18 years.

Take Quiet 50 XR Tablet as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Quiet 50 XR Tablet should be taken at least one hour before meals or prior to bedtime.

Overdose Effects of Quiet 50 XR Tablet

  • Survival reported in overdoses up to 30 grams.
  • No specific antidote; consider intensive care measures.
  • Treat refractory hypotension with intravenous fluids and/or sympathomimetic agents (avoid adrenaline and dopamine).
✔️ Interaction
  • Use caution with drugs causing electrolyte imbalance or QT interval increase.
  • Co-administration with thioridazine, carbamazepine, or phenytoin increases the clearance of Quetiapine.
✔️ Contraindications

Quetiapine should not be used in the following situations:

  1. Allergy: If you are allergic to Quetiapine or any of its components.
  2. Drug Interactions: Avoid Quetiapine if you are taking:
    • Protease inhibitors for HIV (e.g., Atazanavir, Lopinavir).
    • Antifungal medications (e.g., Ketoconazole, Posaconazole, Itraconazole).
    • Certain antibiotics (e.g., Erythromycin, Clarithromycin).
    • Nefazodone is used for depression.
✔️ Pregnancy & Lactation
  • Safety during pregnancy is not established. Use only if benefits justify potential risks.
  • Unknown if excreted in human milk; avoid breastfeeding.
✔️ Precautions & Warnings
  • The risk of suicide and worsening depression persists until significant remission.
  • Use with caution in patients with cardiovascular or cerebrovascular disease, and conditions predisposing to hypotension.
  • Caution in patients with a history of seizures.
  • Monitor for signs of tardive dyskinesia and neuroleptic malignant syndrome.
  • Use caution in patients with a history or family history of QT prolongation.
  • Monitor for neutropenia, hyperglycemia, and diabetes mellitus.
✔️ Storage Conditions:

Store in a cool, dry place away from light. Keep out of reach of children. Do not use after the expiry date.

Frequently Asked Questions (FAQ)

Do not stop the medicine suddenly. It may cause discontinuation symptoms like sleeplessness (insomnia), dizziness, irritability, nausea, vomiting, headache or diarrhea Speak to your doctor if you do not want to take this medicine and he will reduce the dose gradually Self-medication and adjusting the dose on your own is strictly not recommended with this medicine

Quiet 50 XR must be used with caution in elderly patients with dementia.
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Check our pricing section for Quiet 50 XR Tablet 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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